For thousands of years perfume has been used to allay anxieties, to stimulate, to calm, to heal, or for its aphrodisiac or anaphrodisiac properties. Perfumes were so precious they were reserved for sacrifices to the Gods, for kings and their priests who combined the function of advisers and healers. One of the examples that come to mind is the incredibly precious Nard-oil which a woman used to anoint Jesus.
Even today natural perfumes are destilled by vapour from plants. The resulting etheric oils-natural perfumes-work through the nose or they are massaged into the skin. They then enter the body through olfactory receptors of the skin surface, Their action is almost immediate.
Essential oils are lipophilic being made up of very small molecules which are easily absorbed.